PharmaTutor l For Pharmaceutical Industry & Pharma Student

                                               Organization Post Qualification Contact details Last date Dr. Reddy’s Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad. Junior Research Fellow Project :DST-SERB funded project entitled ‘Synthesis of Anticancer Drug Trabectedin and Related Analogues’ Post Graduate Degree in Chemistry (Organic / Medicinal Chemistry) (M.Sc Chemistry) - Post Graduate Degree in Pharmacy / Basic Science (M.Pharm Medicinal Chemistry / Process Chemistry / Pharmaceutics / Pharma Chemistry) NETs accepted : CSIR-NET including LS; GATE, JAM, GPAT, BET, JEST, JGEEBILS, ICMR-JRF and ICAR- AICE hr@drils.org 31st January, 2021 Institute of Advanced Study in Science and Technology (IASST)  Temporary position (contractual) of two (02) Research Scientists and one (01) Technical ass

                                               Biorelevant Media l Hydrodynamics in the GIT   l  API/Formulation properties How a medicine should be taken is usually explained in the patient information leaflet provided by the manufacturer. Whether a drug is taken before or after a meal can have a big impact on its absorption because food changes the properties of gastrointestinal fluids a lot. Gut fluids in both fasted and fed states are simulated by Biorelevant Media. I have already shared the information regarding Fluid composition in the GIT. More details refer link https://pharmatutor21.blogspot.com/2021/01/biorelevant-dissolution-media.html   This blog will help you to understand other two steps i.e. Hydrodynamics in the GIT and API/formulation properties Biorelevant dissolution medium Before the development of biorelevant dissolution medium the following steps should be considered 1)         Fluid composition in the GIT 2)         Hydrodynamics in the GIT 3)         API/formul

                                                    Biorelevant Media How a medicine should be taken is usually explained in the patient information leaflet provided by the manufacturer. Whether a drug is taken before or after a meal can have a big impact on its absorption because food changes the properties of gastrointestinal fluids a lot. Gut fluids in both fasted and fed states are simulated by Biorelevant Media. Why should I test in Biorelevant Media? BE studies are pivotal in showing similarity between a pharmaceutically equivalent generic formulation and the reference listed drug in ANDA submission. Different regulatory agencies have different requirements regarding BE studies for immediate release (IR) products. Refer below link more information https://www.blogger.com/blog/post/edit/2376840283485197087/2192731683837054919 As all of us know, there are few medicines which need to be taken before meal (fasting) and few are after meal (Fed). Whether a drug is taken befor